Projects

FHIT and Bacteriophage Hit-like Proteins

Investigating structural and functional conservation between putative histidine triad (HIT) proteins in bacteriophage and the human tumor suppressor, fragile histdine triad protein (FHIT)

Dr. Kari Clase Lab

Targeted Radiotherapies

Working under the leadership of Dr. Ramesh Mukkamala in the development of fibroblast activation protein (FAP) targeted therapies for the delivery of florescence and radioisotopes to various cancer models

Dr. Philip Low Lab

Image (Figure 6): Mukkamala, R., Lindeman, S. D., Kragness, K. A., Shahriar, I., Srinivasarao, M., & Low, P. S. (2022). Design and characterization of fibroblast activation protein targeted pan-cancer imaging agent for fluorescence-guided surgery of solid tumors. Journal of Materials Chemistry B, 10(12), 2038–2046. https://doi.org/10.1039/D1TB02651H

Conserved Bacteriophage Protein Product Identification

The identification of conserved eukaryotic gene products from novel bacteriophage PurduePete using in-silico techniques

HHMI SEA-PHAGES

Dr. Kari Clase Lab